Nearly half of adults with OA/TOF will have respiratory symptoms each year. In one study, 30% had physician-diagnosed asthma, 44% reported wheezing in the last year, 28% recurrent wheeze, 30% long-standing cough, 25% cough and sputum. (4) This is also reflected in pulmonary function test results, where 21% demonstrate a restrictive pattern, 21% obstructive and 36% both. (5)
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