OA/TOF related respiratory issues for adults

In this live Q&A we were joined by Professor Alyn Morice to answer questions on respiratory issues, such as chronic cough, aspiration, dysmotility and tracheomalacia for those born with OA/TOF.

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01:30 How can I better manage respiratory issues?

08:43 How would you recommend managing day to day when struggling to cough up sputum?

10:27 Do adults born with OA/TOF need to take extra precautions with regards to flu and covid vaccination?

15:30 Which medications would you recommend for an adult with OA/TOF cough?

17:59 Is Gefapixant now available in the UK?

21:08 Can you recommend anything to help with the digestive side effects of Azithromycin?

22:58 What are the side effects from taking PPI’s long term? Could I use it effectively on an ad-hoc basis?

26:10 Can you suggest any breathing and/or swallowing techniques to reduce the “TOF cough”?

29:32 Can Lisdexamfetamine for ADHD reduce TOF cough symptoms?

34:14 What is tracheomalacia?

35:39 Can breathlessness be related to OA/TOF?

40:00 Have you ever seen OA/TOF with portoystemic shunt?

42:07 Do you see teens/adults on purees

44:03 What are your thoughts on feeding intensive programmes?

45:57 How can I access care from you, your team or other specialist in the UK?

49:55 Can you explain tracheal diverticulum?

Meet the speaker

Professor Morice is Head of Respiratory Medicine at HYMS, based at the University of Hull. He is also an Honorary Consultant Physician at Hull and East Yorkshire Hospitals NHS Trust. Professor Morice specialises in the diagnosis and treatment of cough and runs the Hull Cough Clinic. He also runs the Hull Respiratory Clinical Trials Unit, specialising in the treatment of asthma and COPD.

Professor Morice has led the European Respiratory Society and British Thoracic Society Taskforces on Cough.

Some members may recall Professor Morice’s previous talk on the TOF Cough.

Information correct at time of recording (October, 2026). Click here to read our disclaimer.